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Acute headache
Tension‐type headache
1. Acupuncture is effective in the treatment of tension‐type heachache (N) (Level I
[Cochrane Review]).
2. The addition of caffeine to aspirin or paracetamol improves analgesia in the treatment of
episodic tension‐type heachache (U) (Level I).
3. Simple analgesics such as aspirin, paracetamol or NSAIDs, either alone or in combination,
are effective in the treatment of episodic tension‐type heachache (U) (Level II).
SUMMARY 4. Triptans are effective in the treatment of severe migraine (U) (Level I).
Migraine
Aspirin‐metoclopramide is effective in the treatment of mild‐to‐moderate migraine (U)
5.
Parenteral metoclopramide is effective in the treatment of migraine (U) (Level I).
6. (Level I).
7. Over‐the‐counter medications, including combined paracetamol‐aspirin‐caffeine
preparations, are effective in the treatment of migraine with mild‐to‐moderate
symptoms and disability (N) (Level I).
8. Effervescent aspirin, ibuprofen or dipyrone are effective in the treatment of migraine (N)
(Level I).
9. In children or adolescents with migraine, ibuprofen or intranasal sumatriptan (over
12 years of age) are effective treatments (N) (Level I).
10. Pethidine is less effective than most other migraine treatments and should not be used
(N) (Level I).
11. Parenteral prochlorperazine, chlorpromazine or droperidol are effective in the treatment
of migraine, especially in the emergency department (N) (Level II).
12. Paracetamol is effective in the treatment of mild‐to‐moderate migraine (U) (Level II).
13. A ‘stratified care strategy’ is effective in treating migraine (U) (Level II).
Cluster headache
14. Parenteral triptans (sumatriptan or zolmitriptan) (S) or oxygen therapy (U), are effective
treatments for cluster headache attacks (Level II).
Postdural puncture headache
15. There is no evidence that bed rest is beneficial in the treatment and prevention of
postdural puncture headache (U) (Level I [Cochrane Review]).
16. The incidence of postdural puncture headache is reduced by using small‐gauge spinal
needles and/or a non‐cutting bevel (U) (Level I).
17. Further high quality trials are required to determine the efficacy of epidural blood patch
administration in the treatment of postdural puncture headache (U) (Level I), however
benefit is likely (N) (Level II).
Opioids should be used with extreme caution in the treatment of headache (U).
Frequent use of analgesics, triptans and ergot derivatives in the treatment of recurrent
acute headache may lead to medication overuse headache (U).
xxxviii Acute Pain Management: Scientific Evidence

