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G. de Mesquita Araújo: Dor Neuropática Vascular – Dor Fantasma
maioria dos doentes não responde às terapêuti- Jensen TS, Krebs B, Nielsen J, Rasmussen P. Non-painful phantom limb
cas prescritas. phenomena in amputees: incidence, clinical characteristics and
temporal course. Acta Neurol Scand 1984;70(6):407-14.
Os factores periféricos e centrais responsá- Jensen TS, Krebs B, Nielsen J, Rasmussen P. Immediate and long-term
veis pelo aparecimento de dor fantasma estão phantom limb pain in amputees: incidence, clinical characteris-
intimamente ligados. Falta ainda entender a im- tics and relationship to pre-amputation limb pain. Pain 1985;
21(3):267-78.
portância do componente periférico sobre a re- Katz J, Melzack R. Pain “memories” in phantom limbs: review and clinical
organização cortical pós-amputação. A estraté- observations. Pain 1990;43(3):319-36.
gia terapêutica deve ser feita de acordo com os Katz J, Kavanagh BP, Sandler AN, et al. Preemptive analgesia. Clinical
conhecimentos actuais dos mecanismos neuro- evidence of neuroplasticity contributing to postoperative pain. Anes-
thesiology 1992;77(3):439-46.
fisiológicos. Tratamentos mais específicos ne- Kooijman CM, Dijkstra PU, Geertzen JH, et al. Phantom pain and phantom
cessitam de estudos prospectivos controlados sensations in upper limb amputees: an epidemiological study. Pain
2000;87(1):33-41.
para comprovar a sua eficácia. Lacoux PA, Crombie IK, Macrae WA. Pain in traumatic upper limb ampu-
tees in Sierra Leone. Pain 2002;99(1-2):309-12.
Bibliografia Lierz P, Schroegendorfer K, Choi S, et al. Continuous blockade of both
brachial plexus with ropivacaine in phantom pain: a case report.
Ben Abraham R, Marouani N, Weinbroum AA. Dextromethorphan mitiga- Pain 1998;78(2):135-7.
tes phantom pain in cancer amputees. Ann Surg Oncol 2003; Melzack R. Phantom limb pain: implications for treatment of pathologic
10(3):268-74. pain. Anesthesiology 1971;35(4):409-19.
Bach S, Noreng MF, Tjellden NU. Phantom limb pain in amputees during Montoya P, Larbig W, Grulke N, et al. The relationship of phantom limb pain
the first 12 months following limb amputation, after preoperative to other phantom limb phenomena in upper extremity amputees.
lumbar epidural blockade. Pain 1988;33(3):297-301. Pain 1997;72(1-2):87-93.
Bergmans L, Snijdelaar DG, Katz J, Crul BJ. Methadone for phantom limb Nikolajsen L, Hansen CL, Nielsen J, et al. The effect of ketamine on phan-
pain. Clin J Pain 2002;18(3):203-5. tom pain: a central neuropathic disorder maintained by peripheral
Birbaumer N, Lutzenberger W, Montoya P, et al. Effects of regional anesthe- input. Pain 1996;67(1):69-77.
sia on phantom limb pain are mirrored in changes in cortical reorga- Nikolajsen L, Ilkjaer S, Christensen JH, et al. Randomised trial of epidural
nization in upper limbs amputees. J Neurosci 1997;17(14):5503-8. bupivacaine and morphine in prevention of stump and phantom pain
Bone M, Critchley P, Buggy DJ. Gabapentin in postamputation phantom in lower-limb amputation. Lancet 1997;350(9088):1353-7.
limb pain: a randomized, double-blind, placebo-controlled, cross- Nikolajsen L, Ilkjaer S, Kroner K, et al. The influence of preamputation
over study. Reg Anesth Pain Med 2002;27(5):481-6. pain on postamputation stump and phantom pain. Pain 1997;
Dellemijn P. Are opioids effective in relieving neuropathic pain? Pain 1999; 72(3):393-405.
80(3):453-62. Nikolajsen L, Jensen TS. Phantom limb pain. Br J Anaesth 2001;87
Flor H, Elbert T, Knecht S, et al. Phantom-limb pain as a perceptual corre- (1):107-16.
late of cortical reorganization following arm amputation. Nature 1995; Nikolajsen L, Jensen TS. Phantom limb pain. Em: McMahon SB, Koltzen-
375(6531):482-4. burg M, eds. Wall and Melzack’s Textbook of Pain. Elsevier 2006;
Flor H, Denke C, Schaefer M, Grusser S. Effect of sensory discrimination 961-71.
training on cortical reorganisation and phantom limb pain. Lancet Nyström B, Hagbarth KE. Microelectrode recordings from transected ner-
2001;357(9270):1763-4. ves in amputees with phantom limb pain. Neurosci Lett 1981;
Flor H. Phantom-limb pain: characteristics, causes, and treatment. Lancet 27(2):211-6.
Neurol 2002;1(3):182-9. Robinson LR, Czerniecki JM, Ehde DM, et al. Trial of amitriptyline for relief
Flor H. Cortical reorganisation and chronic pain: implications for rehabili- of pain in amputees: results of a randomized controlled study. Arch
tation. J Rehabil Med 2003;41(Suppl):66-72. Phys Med Rehabil 2004;85(1):1-6.
Galhardo V. Mecanismos neurobiológicos da dor fantasma. Dor 2004; Sherman RA, Sherman CJ, Gall NG. A survey of current phantom limb pain
12(1):12-8. treatment in the United States. Pain 1980;8(1):85-99.
Hill A, Niven CA, Knussen C. Pain memories in phantom limbs: a case Sherman RA, Sherman CJ. Prevalence and characteristics of chronic phan-
study. Pain 1996;66(2-3):381-4. tom limb pain among American veterans. Results of a trial survey.
Houghton AD, Nicholls G, Houghton AL, et al. Phantom pain: natural history Am J Phys Med 1983;62(5):227-38.
and association with rehabilitation. Ann R Coll Surg Engl 1994; Sherman RA, Sherman CJ, Parker L. Chronic phantom and stump
76(1):22-5. pain among American veterans: results of a survey. Pain 1984;
Huse E, Larbig W, Flor H, Birbaumer N. The effect of opioids on phantom 18(1):83-95.
limb pain and cortical reorganization. Pain 2001;90(1-2):47-55. Sindrup SH, Jensen TS. Efficacy of pharmacological treatments of neuro-
Jahangiri M, Jayatunga AP, Bradley JW, Dark CH. Prevention of phantom pathic pain: an update and effect related to mechanism of drug
pain after major lower limb amputation by epidural infusion of dia- action. Pain 1999;83(3):389-400.
morphine, clonidine and bupivacaine. Ann R Coll Surg Engl 1994; Wiech K, Töepfner T, Preissl H, et al. Prevention of phantom limb pain and
76(5):324-6. cortical reorganization in the early phase after amputation in hu-
Jenkins WM, Merzenich MM, Ochs MT, et al. Functional reorganization mans. Soc Neurosci Abstr 2001;28:163-9.
of primary somatosensory cortex in adult owl monkeys after be- Woolf CJ, Salter MW. Neuronal plasticity: increasing the gain in pain.
haviorally controlled tactile stimulation. J Neurophysiol 1990; Science 2000;288(5472):1765-9.
63(1):82-104. Wu CL, Tella P, Staats PS, et al. Analgesic effects of intravenous lidocaine
Jensen TS, Krebs B, Nielsen J, Rasmussen P. Phantom limb, phantom pain and morphine on postamputation pain: a randomized double-blind,
and stump pain in amputees during the first 6 months following limb active placebo-controlled, crossover trial. Anesthesiology 2002;
amputation. Pain 1983;17(3):243-56. 96(4):841-8.
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